TargetMol

Macitentan

Product Code:
 
TAR-T2561
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2561-5mg5mg£105.00
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Quantity:
TAR-T2561-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T2561-10mg10mg£119.00
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TAR-T2561-50mg50mg£139.00
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TAR-T2561-100mg100mg£172.00
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Quantity:
TAR-T2561-500mg500mg£309.00
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This product comes from: United States.
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Further Information

Bioactivity:
Macitentan is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).
CAS:
441798-33-0
Formula:
C19H20Br2N6O4S
Molecular Weight:
588.28
Pathway:
GPCR/G Protein; Apoptosis
Purity:
0.9952
SMILES:
CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1
Target:
Apoptosis; Endothelin Receptor

References

1. Iglarz M, et al. J Pharmacol Exp Ther, 2008, 327(3), 736-745. 2. Sen S, et al. Life Sci, 2012, 91(13-14), 658-668. 3. Kim SJ, et al. Neoplasia, 2011, 13(2), 167-179.