TargetMol

TCS PrP Inhibitor 13

Product Code:
 
TAR-T23450
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23450-1mg1mg£99.00
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TAR-T23450-2mg2mg£111.00
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TAR-T23450-5mg5mg£135.00
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TAR-T23450-1mL1 mL * 10 mM (in DMSO)£161.00
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TAR-T23450-10mg10mg£173.00
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TAR-T23450-25mg25mg£303.00
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TAR-T23450-50mg50mg£436.00
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TAR-T23450-100mg100mg£610.00
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Quantity:
TAR-T23450-500mg500mg£1,219.00
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Further Information

Bioactivity:
TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
CAS:
34320-83-7
Formula:
C15H11N3O3
Molecular Weight:
281.271
Purity:
0.9905
SMILES:
[O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1

References

1. Kimata A, et al. New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation [published correction appears in J Med Chem. 2008 Mar 13;51(5):1503]. J Med Chem. 2007;50(21):5053-5056. 2. Provenzano L, et al. Cellular prion protein (PrPC) in the development of Merlin-deficient tumours. Oncogene. 2017;36(44):6132-6142.