TargetMol

Methyl 2,5-dihydroxycinnamate

Product Code:
 
TAR-T22974
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22974-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T22974-5mg5mg£115.00
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TAR-T22974-10mg10mg£148.00
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TAR-T22974-25mg25mg£229.00
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TAR-T22974-50mg50mg£369.00
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TAR-T22974-100mg100mg£517.00
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Further Information

Bioactivity:
Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
CAS:
63177-57-1
Formula:
C10H10O4
Molecular Weight:
194.186
Pathway:
Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Purity:
0.9898
SMILES:
COC(=O)C=Cc1cc(O)ccc1O
Target:
EGFR

References

1. Sargeant P, Farndale RW, Sage SO. ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem. 1993 Aug 25;268(24):18151-6. 2. Sargeant P, Farndale RW, Sage SO. The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets. FEBS Lett. 1993 Jan 11;315(3):242-6.