TargetMol

GNE-617 hydrochloride (1362154-70-8 free base)

Product Code:
 
TAR-T22801
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22801-2mg2mg£199.00
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Quantity:
TAR-T22801-5mg5mg£261.00
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TAR-T22801-10mg10mg£368.00
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TAR-T22801-50mg50mg£824.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50: 0.54nM to 4.69nM).
CAS:
T22801
Formula:
C21H16ClF2N3O3S
Molecular Weight:
463.88
Purity:
0.98
SMILES:
FC1=CC(F)=CC(S(C2=CC=C(C/N=C(O)/C3=CN4C=CN=C4C=C3)C=C2)(=O)=O)=C1.Cl