TargetMol

XAP044

Product Code:
 
TAR-T21995
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21995-1mg1mg£115.00
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TAR-T21995-2mg2mg£134.00
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TAR-T21995-5mg5mg£163.00
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TAR-T21995-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T21995-10mg10mg£246.00
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TAR-T21995-25mg25mg£383.00
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TAR-T21995-50mg50mg£542.00
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TAR-T21995-100mg100mg£744.00
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Further Information

Bioactivity:
XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].
CAS:
196928-50-4
Formula:
C15H9IO4
Molecular Weight:
380.137
Pathway:
Neuroscience
Purity:
0.9956
SMILES:
Oc1ccc2c(c1)occ(Oc1ccc(I)cc1)c2=O
Target:
GluR

References

1. C. E. Gee, D. Peterlik, C. Neuh user, et al. Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior. The Journal of Biological Chemisty 289(16), 10975-10987 (2014).