TargetMol

VU0483605

Product Code:
 
TAR-T21747
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21747-1mg1mg£103.00
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TAR-T21747-2mg2mg£117.00
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TAR-T21747-5mg5mg£148.00
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TAR-T21747-1mL1 mL * 10 mM (in DMSO)£166.00
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TAR-T21747-10mg10mg£201.00
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TAR-T21747-25mg25mg£329.00
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Quantity:
TAR-T21747-50mg50mg£470.00
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TAR-T21747-100mg100mg£670.00
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TAR-T21747-200mg200mg£863.00
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Quantity:
TAR-T21747-500mg500mg£1,291.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
CAS:
1623101-11-0
Formula:
C20H10Cl3N3O3
Molecular Weight:
446.67
Pathway:
Neuroscience
Purity:
0.9703
SMILES:
O=C(NC1=CC=C(C(Cl)=C1)N2C(=O)C=3C=CC=C(Cl)C3C2=O)C4=NC=CC=C4Cl
Target:
GluR

References

1. Cho HP, Garcia-Barrantes PM, Brogan JT, et al. Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics. ACS Chem Biol. 2014;9(10):2334-2346.