TargetMol

5-fluoro 203

Product Code:
 
TAR-T21704
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21704-1mg1mg£102.00
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TAR-T21704-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T21704-5mg5mg£145.00
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TAR-T21704-10mg10mg£189.00
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TAR-T21704-25mg25mg£309.00
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TAR-T21704-50mg50mg£436.00
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Quantity:
TAR-T21704-100mg100mg£610.00
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Quantity:
TAR-T21704-500mg500mg£1,179.00
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Quantity:
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Further Information

Bioactivity:
5-fluoro 203 is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.
CAS:
260443-89-8
Formula:
C14H11FN2S
Molecular Weight:
258.31
Purity:
0.9802
SMILES:
Cc1cc(ccc1N)-c1nc2cc(F)ccc2s1

References

1. Mclean L S , Watkins C N , Campbell P , et al. Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells[J]. Chemical Research in Toxicology, 2015, 28(5):855-71.