TargetMol

Pyr3

Product Code:
 
TAR-T16687
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16687-1mg1mg£95.00
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TAR-T16687-2mg2mg£106.00
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TAR-T16687-5mg5mg£127.00
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TAR-T16687-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-T16687-10mg10mg£149.00
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TAR-T16687-25mg25mg£252.00
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TAR-T16687-50mg50mg£377.00
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TAR-T16687-100mg100mg£503.00
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TAR-T16687-200mg200mg£695.00
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TAR-T16687-500mg500mg£1,018.00
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Further Information

Bioactivity:
Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM).
CAS:
1160514-60-2
Formula:
C16H11Cl3F3N3O3
Molecular Weight:
456.63
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
O=C(OCC)C=1C=NN(C2=CC=C(C=C2)NC(=O)C(Cl)=C(Cl)Cl)C1C(F)(F)F
Target:
TRP/TRPV Channel

References

1. Kiyonaka S, et al. Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5400-5.