TargetMol

Org-26576

Product Code:
 
TAR-T16402
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16402-2mg2mg£103.00
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TAR-T16402-5mg5mg£124.00
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TAR-T16402-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T16402-10mg10mg£156.00
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TAR-T16402-25mg25mg£213.00
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TAR-T16402-50mg50mg£276.00
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Quantity:
TAR-T16402-100mg100mg£432.00
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Further Information

Bioactivity:
Org-26576 is a positive allosteric modulator of the AMPA receptor.
CAS:
1026791-61-6
Formula:
C11H12N2O2
Molecular Weight:
204.229
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9994
SMILES:
[H][C@@]12CCCN1C(=O)c1cccnc1OC2
Target:
GluR; iGluR

References

1. Jordan GR, et al. Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography. Neuropharmacology. 2005 Aug;49(2):254-64. 2. Su XW, et al. Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus. Psychopharmacology (Berl). 2009 Oct;206(2):215-22. 3. Fumagalli F, et al. The AMPA receptor potentiator Org 26576 modulates stress-induced transcription of BDNF isoforms in rat hippocampus. Pharmacol Res. 2012 Feb;65(2):176-81.