TargetMol

Dynarrestin

Product Code:
 
TAR-T15183
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15183-2mg2mg£115.00
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TAR-T15183-5mg5mg£144.00
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TAR-T15183-1mL1 mL * 10 mM (in DMSO)£160.00
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TAR-T15183-10mg10mg£197.00
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TAR-T15183-25mg25mg£286.00
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TAR-T15183-50mg50mg£401.00
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Further Information

Bioactivity:
Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis .
CAS:
2222768-84-3
Formula:
C22H23F2N3O2S
Molecular Weight:
431.5
Pathway:
Stem Cells; GPCR/G Protein
Purity:
0.9949
SMILES:
CCOC(=O)c1sc(Nc2ccc(F)cc2F)nc1-c1ccc(cc1)N(CC)CC
Target:
Hedgehog/Smoothened

References

1. H?ing S, et al. Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein. Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6.