TargetMol

DNA2 inhibitor C5

Product Code:
 
TAR-T15146
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15146-1mg1mg£115.00
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TAR-T15146-2mg2mg£132.00
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TAR-T15146-1mL1 mL * 10 mM (in DMSO)£168.00
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TAR-T15146-5mg5mg£168.00
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TAR-T15146-10mg10mg£230.00
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TAR-T15146-25mg25mg£436.00
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TAR-T15146-50mg50mg£610.00
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TAR-T15146-100mg100mg£838.00
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Quantity:
TAR-T15146-500mg500mg£1,613.00
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Further Information

Bioactivity:
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
CAS:
35973-25-2
Formula:
C10H6N2O5
Molecular Weight:
234.167
Purity:
0.98
SMILES:
OC(=O)c1cnc2c(cccc2c1O)[N+]([O-])=O

References

1. Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.