TargetMol

DM4

Product Code:
 
TAR-T15141
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15141-1mg1mg£95.00
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TAR-T15141-2mg2mg£106.00
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TAR-T15141-5mg5mg£128.00
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TAR-T15141-1mL1 mL * 10 mM (in DMSO)£163.00
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TAR-T15141-10mg10mg£177.00
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TAR-T15141-25mg25mg£275.00
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Quantity:
TAR-T15141-50mg50mg£430.00
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This product comes from: United States.
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Further Information

Bioactivity:
DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
CAS:
796073-69-3
Formula:
C38H54ClN3O10S
Molecular Weight:
780.37
Pathway:
Cytoskeletal Signaling;
Purity:
0.9815
SMILES:
[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)C=C/C=C(C)Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)S)[C@]1(C)O[C@H]1[C@@H]2C
Target:
Microtubule Associated

References

1. Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.