TargetMol

C 87

Product Code:
 
TAR-T14848
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14848-1mg1mg£103.00
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TAR-T14848-2mg2mg£118.00
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TAR-T14848-5mg5mg£148.00
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TAR-T14848-1mL1 mL * 10 mM (in DMSO)£157.00
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TAR-T14848-10mg10mg£189.00
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TAR-T14848-25mg25mg£309.00
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TAR-T14848-50mg50mg£511.00
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TAR-T14848-100mg100mg£704.00
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Further Information

Bioactivity:
C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.
CAS:
332420-90-3
Formula:
C24H15ClN6O3S
Molecular Weight:
502.93
Pathway:
; Apoptosis
Purity:
0.98
SMILES:
[O-][N+](=O)c1cc(NN=C2C(=O)N(N=C2c2ccccc2)c2nc(cs2)-c2ccccc2)ccc1Cl
Target:
TNF

References

1. Ma L, et al. A novel small-molecule tumor necrosis factor ? inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289(18):12457-66.