TargetMol

Tecalcet Hydrochloride

Product Code:
 
TAR-T13918
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13918-1mg1mg£95.00
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TAR-T13918-2mg2mg£106.00
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TAR-T13918-5mg5mg£127.00
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TAR-T13918-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T13918-10mg10mg£164.00
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TAR-T13918-25mg25mg£282.00
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TAR-T13918-50mg50mg£414.00
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TAR-T13918-100mg100mg£571.00
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TAR-T13918-200mg200mg£779.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tecalcet Hydrochloride is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
CAS:
177172-49-5
Formula:
C18H23Cl2NO
Molecular Weight:
340.29
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
Cl.COc1cccc(c1)[C@@H](C)NCCCc1ccccc1Cl
Target:
CaSR

References

1. Wada, M., et al. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. Journal of Clinical Investigation 100(12), 2977-2983 (1997). 2. Nemeth, E.F., et al. The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatr.Nephrol. 10(3), 275-279 (1996). 3. Nemeth, E.F., et al. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proceedings of the National Academy of Sciences of the United States of America 95(7), 4040-4045 (1998).