TargetMol

Tunicamycin

Product Code:
 
TAR-T13229
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T13229-50mg50mgEnquire
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TAR-T13229-1mg1mg£173.00
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TAR-T13229-5mg5mg£326.00
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TAR-T13229-10mg10mg£505.00
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TAR-T13229-25mg25mg£772.00
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Further Information

Bioactivity:
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.
CAS:
11089-65-9
Formula:
C30H46N4O16
Molecular Weight:
718.71
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CC(C)CC=CC(=O)N[C@@H]1C(O[C@H]2OC(CO)[C@@H](O)[C@H](O)C2NC(C)=O)O[C@@H](CC(O)[C@H]2O[C@H](C(O)[C@H]2O)n2ccc(=O)[nH]c2=O)C(O)[C@H]1O
Target:
Influenza Virus; Antibacterial; Antibiotic; Antifungal

References

1. Hsu JL, et al. Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):373-82. 2. Hou H, et al. DPAGT1/Akt/ABCG2 pathway in mouse Xenograft models of human hepatocellular carcinoma. Mol Cancer Ther. 2013 Dec;12(12):2874-84. 3. Han C, et al. Endoplasmic reticulum stress inhibits cell cycle progression via induction of p27 in melanoma cells. Cell Signal. 2013 Jan;25(1):144-9.