TargetMol

Polyinosinic-polycytidylic acid sodium

Product Code:
 
TAR-T12516
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12516-1mg1mg£101.00
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TAR-T12516-2mg2mg£114.00
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TAR-T12516-5mg5mg£141.00
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TAR-T12516-10mg10mg£182.00
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TAR-T12516-25mg25mg£269.00
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TAR-T12516-50mg50mg£366.00
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Quantity:
TAR-T12516-100mg100mg£507.00
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Quantity:
TAR-T12516-500mg500mg£1,002.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Polyinosinic-polycytidylic acid sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5).
CAS:
42424-50-0
Formula:
C19H28N7NaO16P2
Molecular Weight:
695.403
Pathway:
; Apoptosis; Immunology/Inflammation
Purity:
0.98
SMILES:
[NaH].Nc1ccn([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1.O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1nc[nH]c2=O
Target:
Apoptosis; TLR

References

1. Besch R, et al. Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J Clin Invest. 2009 Aug;119(8):2399-411. 2. Cheng YS, et al. Anticancer function of polyinosinic-polycytidylic acid. Cancer Biol Ther. 2010 Dec 15;10(12):1219-23.