TargetMol

NBDHEX

Product Code:
 
TAR-T12189
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12189-1mg1mg£95.00
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TAR-T12189-2mg2mg£106.00
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TAR-T12189-5mg5mg£128.00
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TAR-T12189-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T12189-10mg10mg£168.00
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TAR-T12189-25mg25mg£249.00
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TAR-T12189-50mg50mg£369.00
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TAR-T12189-100mg100mg£519.00
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This product comes from: United States.
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Further Information

Bioactivity:
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).
CAS:
787634-60-0
Formula:
C12H15N3O4S
Molecular Weight:
297.33
Pathway:
Apoptosis; Autophagy; Metabolism
Purity:
0.9694
SMILES:
OCCCCCCSc1ccc([N+]([O-])=O)c2nonc12
Target:
Apoptosis; Glutathione Peroxidase; Autophagy

References

1. Filomeni G, et al. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer. Mol Cancer Ther. 2008 Feb;7(2):371-9. 2. Sha HH, et al. 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound. Biosci Rep. 2018 Feb 13;38(1). pii: BSR20171440.