TargetMol

DCZ0415

Product Code:
 
TAR-T10981
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10981-1mg1mg£109.00
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TAR-T10981-2mg2mg£128.00
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TAR-T10981-5mg5mg£165.00
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TAR-T10981-1mL1 mL * 10 mM (in DMSO)£173.00
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TAR-T10981-10mg10mg£230.00
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TAR-T10981-25mg25mg£422.00
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TAR-T10981-50mg50mg£589.00
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TAR-T10981-100mg100mg£809.00
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This product comes from: United States.
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Further Information

Bioactivity:
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit NF-κB activity.
CAS:
2242470-43-3
Formula:
C23H20N2O2
Molecular Weight:
356.425
Pathway:
Apoptosis; ; NF-κb
Purity:
0.991
SMILES:
O=C1C2C(C3C=CC2C2CC32)C(=O)N1c1ccc(Cc2ccncc2)cc1
Target:
Apoptosis; NF-κB

References

1. Wang Y, et al. A Small Molecule Inhibitor Targeting TRIP13 suppresses multiple myeloma progression. Cancer Res. 2019 Nov 15. pii: canres.3987.2018.