TargetMol

AR-13324 analog mesylate

Product Code:
 
TAR-T10357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T10357-100mg100mgEnquire
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TAR-T10357-200mg200mgEnquire
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TAR-T10357-2mg2mg£238.00
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TAR-T10357-5mg5mg£320.00
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TAR-T10357-1mL1 mL * 10 mM (in DMSO)£417.00
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TAR-T10357-10mg10mg£426.00
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TAR-T10357-50mg50mg£1,133.00
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Further Information

Bioactivity:
AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.
CAS:
T10357
Formula:
C29H33N3O9S2
Molecular Weight:
631.72
Purity:
0.98
SMILES:
CS(=O)(O)=O.CS(=O)(O)=O.O=C(OC1=CC=C([C@@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C

References

1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. 2. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.