TargetMol

Kamebakaurin

Product Code:
 
TAR-TWS1977
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TWS1977-1mg1mg£151.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TWS1977-5mg5mg£340.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
1. Kamebakaurin has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. 3. Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50.4. Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.
CAS:
73981-34-7
Formula:
C20H30O5
Molecular Weight:
350.455
Pathway:
NF-κb
Purity:
0.9805
SMILES:
CC1(C)CC[C@H](O)[C@@]2(CO)[C@@H]3CC[C@@H]4[C@H](O)[C@@]3([C@H](O)C[C@H]12)C(=O)C4=C
Target:
NF-κB

References

Wang K S , Lee J J . Kamebakaurin inhibits the expression of hypoxia-inducible factor-1? and its target genes to confer antitumor activity[J]. Oncology Reports, 2016, 35(4):2045.