TargetMol

TLQP 21 acetate

Product Code:
 
TAR-TP2296L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP2296L-1mg1mg£219.00
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TAR-TP2296L-5mg5mg£436.00
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TAR-TP2296L-10mg10mg£687.00
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TAR-TP2296L-25mg25mg£1,177.00
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TAR-TP2296L-50mg50mg£1,734.00
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This product comes from: United States.
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Further Information

Bioactivity:
TLQP 21 acetate is a potent agonist of G-protein-coupled receptor complement-3a receptor 1 (C3aR1). The EC50 values are 10.3 μM for mouse and 68.8 μM for human. TLQP 21 acetate is a VGF-derived peptide with endocrine and extraendocrine properties.
CAS:
0
Formula:
C109H174N40O28
Molecular Weight:
2492.8
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
CC(O)=O.N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC([C@H]1N(C([C@H]2N(C([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC3=CNC=N3)NC([C@H](CC4=CNC=N4)NC([C@H](CC5=CC=CC=C5)NC([C@H](CC6=CNC=N6)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CO)NC([C@H](C)NC([C@H]7N(C([C@H]8N(C([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)N)=O)=O)=O)CCC8)=O)CCC7)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)CCC1)=O)=O
Target:
Complement System

References

Elena Bresciani , et al. TLQP-21, A VGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In Vitro Calcium Signaling. Int J Mol Sci. 2019 Dec 24;21(1):130. Cheryl Cero, et al. The TLQP-21 Peptide Activates the G-protein-coupled Receptor C3aR1 via a Folding-Upon-Binding Mechanism. ructure. 2014 Dec 2;22(12):1744-1753.