TargetMol

R18

Product Code:
 
TAR-TP2127
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP2127-1mg1mg£364.00
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Further Information

Bioactivity:
Antagonist of 14.3.3 proteins (KD ?80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
CAS:
211364-78-2
Formula:
C101H157N27O29S3
Molecular Weight:
2309.69
Purity:
0.98
SMILES:
0

References

Wang et al (1999) Isolation of high-affinity peptide antagonists of 14.3.3 proteins by phage display. Biochemistry 38 12499 PMID: Masters and Fu (2001) 14.3.3 proteins mediate an essential anti-apoptotic signal. J.Biol.Chem. 276 45193 PMID: