TargetMol

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Product Code:
 
TAR-TP1924
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1924-1mg1mg£146.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TP1924-5mg5mg£229.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TP1924-10mg10mg£331.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.
CAS:
863987-12-6
Formula:
C90H154N30O17
Molecular Weight:
1928.4
Purity:
0.98
SMILES:
0

References

Pastalkova et al (2006) Storage of spatial information by the maintenance mechanism of LTP. Science 313 1141 PMID: Serrano et al (2005) Persistent phosphorylation by protein kinase Mz maintains late-phase long-term potentiation. J.Neurosci. 25 1979 PMID: