TargetMol

Histatin 5 acetate

Product Code:
 
TAR-TP1741L
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1741L-1mg1mg£214.00
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TAR-TP1741L-5mg5mg£426.00
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TAR-TP1741L-10mg10mg£595.00
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TAR-TP1741L-25mg25mg£863.00
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TAR-TP1741L-50mg50mg£1,187.00
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TAR-TP1741L-100mg100mg£1,581.00
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Further Information

Bioactivity:
Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
CAS:
TP1741L
Formula:
C135H199N51O35
Molecular Weight:
3096.35
Pathway:
Proteases/Proteasome
Purity:
0.9872
SMILES:
OC([C@@H](NC(CNC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](NC([C@@H](NC([C@H](CO)NC([C@@H](N)CC(O)=O)=O)=O)CC1=CN=CN1)=O)C)=O)=O)=O)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)CC5=CC=CC=C5)=O)CC6=CN=CN6)=O)=O)=O)CC7=CN=CN7)=O)CC8=CN=CN8)=O)=O)CC9=CN=CN9)=O)=O)=O)CC%10=CC=C(O)C=C%10)=O.CC(O)=O
Target:
MMP

References

Gusman H, et al. Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontaldisease. Infect Immun. 2001 Mar;69(3):1402-8. Helmerhorst EJ, et al. The human salivary peptide histatin 5 exerts its antifungal activity through the formation ofreactive oxygen species. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14637-42.