TargetMol

ATI-2341 TFA (1337878-62-2 free base)

Product Code:
 
TAR-TP1354
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1354-1mg1mg£160.00
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TAR-TP1354-5mg5mg£327.00
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TAR-TP1354-10mg10mg£475.00
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This product comes from: United States.
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Further Information

Bioactivity:
ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).
CAS:
TP1354
Formula:
C106H179F3N26O27S2
Molecular Weight:
2370.84
Purity:
0.98
SMILES:
0

References

Quoyer J, et al. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):E5088-97.