TargetMol

(-)-Epipodophyllotoxin

Product Code:
 
TAR-TN7041
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN7041-1mg1mg£104.00
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TAR-TN7041-5mg5mg£148.00
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TAR-TN7041-10mg10mg£189.00
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Further Information

Bioactivity:
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro.
CAS:
4375-07-9
Formula:
C44H42O16
Molecular Weight:
826.79
Pathway:
Apoptosis
Purity:
0.9997
SMILES:
COc1cc([C@@H]([C@H]([C@H](CO2)[C@@H]3O)C2=O)c2c3cc3OCOc3c2)cc(OC)c1OCCOc1cc([C@@H]([C@H]([C@H](CO2)[C@@H]3O)C2=O)c2c3cc3OCOc3c2)cc(OC)c1OC
Target:
Apoptosis

References

Magedov IV, et, al. Reengineered epipodophyllotoxin. Chem Commun (Camb). 2012 Oct 28; 48(84): 10416-8.