TargetMol

Tectol

Product Code:
 
TAR-TN6512
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN6512-1mg1mg£158.00
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TAR-TN6512-5mg5mg£286.00
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TAR-TN6512-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-TN6512-10mg10mg£389.00
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TAR-TN6512-25mg25mg£603.00
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Further Information

Bioactivity:
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44?0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
CAS:
24449-39-6
Formula:
C30H26O4
Molecular Weight:
450.52
Pathway:
Microbiology/Virology; Metabolism
Purity:
0.9923
SMILES:
CC(C)(C=C1)Oc(c2ccccc22)c1c(-c(c1c(c3ccccc33)OC(C)(C)C=C1)c3O)c2O
Target:
Transferase; Parasite

References

Costa SM, et al. Chemical constituents from Lippia sidoides and cytotoxic activity. J Nat Prod. 2001 Jun;64(6):792-5. Cadelis MM, et al. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors. Bioorg Med Chem. 2016;24(14):3102-3107.