TargetMol

Gardenin A

Product Code:
 
TAR-TN4114
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN4114-1mg1mg£229.00
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TAR-TN4114-5mg5mg£465.00
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TAR-TN4114-1mL1 mL * 10 mM (in DMSO)£495.00
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TAR-TN4114-10mg10mg£657.00
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TAR-TN4114-25mg25mg£978.00
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TAR-TN4114-50mg50mg£1,299.00
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TAR-TN4114-100mg100mg£1,661.00
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TAR-TN4114-500mg500mg£3,388.00
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Further Information

Bioactivity:
Gardenin A has antihyperlipidemic and hepatoprotective effects , it also promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent, but not TrkA-dependent, CREB signaling pathways in PC12 cells.
CAS:
21187-73-5
Formula:
C21H22O9
Molecular Weight:
418.4
Pathway:
Tyrosine Kinase/Adaptors; Metabolism; MAPK; Chromatin/Epigenetic; Cytoskeletal Signaling
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1OC)-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1
Target:
ERK; LDL; MAPK; PKA; PKC

References

Chiu SP, et al. Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells. J Agric Food Chem. 2013 Oct 2;61(39):9453-63. Alonso-Castro AJ, et al. Evaluation of the neuropharmacological effects of Gardenin A in mice. Drug Dev Res. 2020 Aug;81(5):600-608.