TargetMol

Taccalonolide B

Product Code:
 
TAR-TN2256
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN2256-50mg50mgEnquire
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TAR-TN2256-1mg1mg£135.00
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TAR-TN2256-5mg5mg£229.00
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TAR-TN2256-10mg10mg£342.00
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TAR-TN2256-25mg25mg£525.00
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Further Information

Bioactivity:
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
CAS:
108885-69-4
Formula:
C34H44O13
Molecular Weight:
660.713
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
[H][C@@]12[C@H](O)[C@@]3([H])[C@]4([H])[C@@H](O)C(=O)[C@@]5([H])C[C@@H]6O[C@@H]6[C@H](OC(C)=O)[C@]5(C)[C@@]4([H])[C@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(C)[C@@]1([H])[C@H](C)C=C1OC(=O)[C@@](C)(O)[C@]21C
Target:
Microtubule Associated

References

Potent Taccalonolides, AF and AJ, Inform Significant Structure??Activity Relationships and Tubulin as the Binding Site of These Microtubule StabilizersJ. Am. Chem. Soc., 2011, 133 (47), pp 19064??19067