TargetMol

Scoulerine

Product Code:
 
TAR-TN2190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2190-1mg1mg£242.00
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TAR-TN2190-2mg2mg£326.00
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TAR-TN2190-5mg5mg£500.00
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TAR-TN2190-10mg10mg£683.00
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TAR-TN2190-25mg25mg£978.00
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Quantity:
TAR-TN2190-50mg50mg£1,315.00
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This product comes from: United States.
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Further Information

Bioactivity:
Scoulerine is an inhibitor of ?-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.
CAS:
6451-73-6
Formula:
C19H21NO4
Molecular Weight:
327.38
Pathway:
Microbiology/Virology; Neuroscience; Apoptosis
Purity:
0.9922
SMILES:
COc1cc2CCN3Cc4c(C[C@H]3c2cc1O)ccc(OC)c4O
Target:
Apoptosis; Beta-Secretase; BACE; Parasite

References

Chlebek J, et al. Cytotoxicity of Naturally Occurring Isoquinoline Alkaloids of Different Structural Types. Nat Prod Commun. 2016 Jun;11(6):753-6. Habartova K, et al. Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells. Sci Rep. 2018;8(1):4829. Published 2018 Mar 19.