TargetMol

Pimaric acid

Product Code:
 
TAR-TN2075
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2075-5mg5mg£279.00
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Quantity:
TAR-TN2075-1mL1 mL * 10 mM (in DMSO)£295.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α?-induced human aortic smooth muscle cells.
CAS:
127-27-5
Formula:
C20H30O2
Molecular Weight:
302.458
Pathway:
MAPK; Proteases/Proteasome; NF-κb
Purity:
0.98
SMILES:
C[C@]1(CC[C@H]2C(CC[C@@H]3[C@]2(C)CCC[C@@]3(C)C(O)=O)=C1)C=C
Target:
MMP; p38 MAPK; NF-κB

References

Pimaric acid from Aralia cordata has an inhibitory effect on TNF-??-induced MMP-9 production and HASMC migration via down-regulated NF-?B and AP-1.Chem Biol Interact. 2012 Aug 30;199(2):112-9.