TargetMol

Nothofagin

Product Code:
 
TAR-TN1996
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1996-1mg1mg£463.00
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TAR-TN1996-5mg5mg£946.00
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TAR-TN1996-1mL1 mL * 10 mM (in DMSO)£1,058.00
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TAR-TN1996-10mg10mg£1,259.00
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TAR-TN1996-25mg25mg£1,862.00
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TAR-TN1996-50mg50mg£2,424.00
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TAR-TN1996-100mg100mg£3,259.00
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This product comes from: United States.
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Further Information

Bioactivity:
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
CAS:
11023-94-2
Formula:
C21H24O10
Molecular Weight:
436.413
Pathway:
Immunology/Inflammation; MAPK; Apoptosis
Purity:
0.98
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c(C(=O)CCc2ccc(O)cc2)c1O
Target:
ERK; IL Receptor; TNF

References

Wonhwa Lee, et al. Anti-inflammatory Effects of Aspalathin and Nothofagin From Rooibos (Aspalathus Linearis) In Vitro and In Vivo. Inflammation. 2015 Aug;38(4):1502-16 de Almeida CLB, et al. Prolonged diuretic and saluretic effect of nothofagin isolated from Leandra dasytricha (A. Gray) Cogn. leaves in normotensive and hypertensive rats: Role of antioxidant system and renal protection. Chem Biol Interact. 2018 Jan 5;279:227-233.