TargetMol

Mesaconine

Product Code:
 
TAR-TN1923
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1923-1mg1mg£254.00
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TAR-TN1923-5mg5mg£519.00
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TAR-TN1923-1mL1 mL * 10 mM (in DMSO)£596.00
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Further Information

Bioactivity:
Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression.
CAS:
6792-09-2
Formula:
C24H39NO9
Molecular Weight:
485.574
Pathway:
NF-κb; Immunology/Inflammation
Purity:
0.98
SMILES:
COC[C@]12CN(C)[C@@H]3[C@@H]4[C@H](OC)[C@H]1[C@]3([C@@H]1C[C@@]3(O)[C@H](O)[C@@H]1[C@]4(O)[C@@H](O)[C@@H]3OC)[C@H](C[C@H]2O)OC
Target:
IL Receptor; NF-κB

References

Identification of NF-?B inhibitors following Shenfu injection and bioactivity-integrated UPLC/Q-TOF-MS and screening for related anti-inflammatory targets in vitro and in silico.J Ethnopharmacol. 2016 Dec 24;194:658-667. Liu X, et al. The in vivo pharmacokinetics, tissue distribution and excretion investigation of mesaconine in rats and its in vitro intestinal absorption study using UPLC-MS/MS. Xenobiotica. 2019 Jan;49(1):71-79.