TargetMol

Isocryptotanshinone

Product Code:
 
TAR-TN1775
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1775-5mg5mg£705.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1775-1mL1 mL * 10 mM (in DMSO)£721.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1?6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
CAS:
22550-15-8
Formula:
C19H20O3
Molecular Weight:
296.366
Pathway:
MAPK; Stem Cells; JAK/STAT signaling
Purity:
0.98
SMILES:
C[C@@H]1COC2=C1C(=O)c1ccc3c(CCCC3(C)C)c1C2=O
Target:
ERK; JNK; STAT

References

Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells.J Breast Cancer. 2015 Jun; 18(2): 112??118.