TargetMol

Ergosta-4,6,8(14),22-tetraen-3-one

Product Code:
 
TAR-TN1617
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN1617-1mg1mg£325.00
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Further Information

Bioactivity:
Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment.
CAS:
19254-69-4
Formula:
C28H40O
Molecular Weight:
392.627
Pathway:
Proteases/Proteasome; Apoptosis
Purity:
0.98
SMILES:
CC(C)[C@@H](C)C=C[C@@H](C)[C@H]1CCC2=C3C=CC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
BCL; Caspase; p53

References

Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.Biochim Biophys Acta. 2011 Apr;1810(4):384-90.