TargetMol

KCNQ1 activator-1?

Product Code:
 
TAR-T9778
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9778-1mg1mg£197.00
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TAR-T9778-5mg5mg£389.00
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TAR-T9778-1mL1 mL * 10 mM (in DMSO)£422.00
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TAR-T9778-10mg10mg£551.00
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TAR-T9778-25mg25mg£1,026.00
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Quantity:
TAR-T9778-50mg50mg£1,508.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- is a potent KCNQ1 channel activator that can be used in long QT syndrome (LQTS) studies.
CAS:
1008671-38-2
Formula:
C22H23N3O4S2
Molecular Weight:
457.57
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
COc(cc1)ccc1-c1csc(NC(C(CCCC2)N2S(c2ccccc2)(=O)=O)=O)n1
Target:
Potassium Channel

References

Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941.