TargetMol

CC618

Product Code:
 
TAR-T9767
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9767-1mg1mg£227.00
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TAR-T9767-5mg5mg£422.00
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TAR-T9767-1mL1 mL * 10 mM (in DMSO)£514.00
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TAR-T9767-10mg10mg£589.00
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TAR-T9767-25mg25mg£863.00
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TAR-T9767-50mg50mg£1,179.00
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Quantity:
TAR-T9767-100mg100mg£1,564.00
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TAR-T9767-500mg500mg£3,058.00
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Further Information

Bioactivity:
CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.
CAS:
1680204-90-3
Formula:
C20H15F6N3O3S2
Molecular Weight:
523.47
Pathway:
DNA Damage/DNA Repair; Metabolism
Purity:
0.9937
SMILES:
Cc1c(C(NCCS(c2ncc(C(F)(F)F)cc2)(=O)=O)=O)sc(-c2ccc(C(F)(F)F)cc2)n1
Target:
PPAR

References

Kaupang ?, et al. Synthesis, biological evaluation and molecular modeling studies of the PPAR?/? antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36. Kaupang ?, et al. Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPAR?/? antagonists: Effects on the affinity and selectivity towards PPAR?/?. Bioorg Med Chem. 2016 Jan 15;24(2):247-60.