TargetMol

MRT-81

Product Code:
 
TAR-T9532
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T9532-1mg1mg£140.00
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TAR-T9532-2mg2mg£173.00
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TAR-T9532-5mg5mg£242.00
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TAR-T9532-1mL1 mL * 10 mM (in DMSO)£281.00
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TAR-T9532-10mg10mg£346.00
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TAR-T9532-25mg25mg£539.00
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TAR-T9532-50mg50mg£740.00
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TAR-T9532-100mg100mg£994.00
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Quantity:
TAR-T9532-500mg500mg£1,910.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
CAS:
1263132-08-6
Formula:
C31H29N3O5S
Molecular Weight:
555.65
Purity:
0.9831
SMILES:
COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1ccc(C)c(NC(=O)c2ccc(cc2)-c2ccccc2)c1

References

Solinas A, et al. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. J Med Chem. 2012 Feb 23;55(4):1559-71.