TargetMol

ART558

Product Code:
 
TAR-T9275
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9275-1mg1mg£201.00
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Quantity:
TAR-T9275-5mg5mg£402.00
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TAR-T9275-10mg10mg£567.00
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TAR-T9275-25mg25mg£862.00
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TAR-T9275-50mg50mg£1,139.00
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Quantity:
TAR-T9275-100mg100mg£1,508.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Pol? inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer.
CAS:
2603528-97-6
Formula:
C21H21F3N4O2
Molecular Weight:
418.41
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
C(N(C)C1=CC(C)=CC=C1)(=O)[C@H]2N(CC[C@H]2O)C3=C(C#N)C(C(F)(F)F)=CC(C)=N3
Target:
DNA/RNA Synthesis

References

Zatreanu D, et al. Pol? inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17;12(1):3636.