TargetMol

PF-05221304

Product Code:
 
TAR-T9209
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9209-1mg1mg£186.00
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TAR-T9209-5mg5mg£306.00
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TAR-T9209-10mg10mg£425.00
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TAR-T9209-1mL1 mL * 10 mM (in DMSO)£432.00
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TAR-T9209-25mg25mg£687.00
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Quantity:
TAR-T9209-50mg50mg£870.00
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Quantity:
TAR-T9209-100mg100mg£1,235.00
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Quantity:
TAR-T9209-200mg200mg£1,637.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
CAS:
1370448-25-1
Formula:
C28H30N4O5
Molecular Weight:
502.571
Pathway:
Metabolism
Purity:
0.9919
SMILES:
COc1cc(cc(n1)-c1ccc(cc1)C(O)=O)C(=O)N1CCC2(CC1)Cc1cnn(C(C)C)c1C(=O)C2
Target:
Acetyl-CoA Carboxylase

References

Ross T T , Crowley C , Kelly K L , et al. Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems[J]. Cellular and Molecular Gastroenterology and Hepatology, 2020, 10(4).