TargetMol

LUF6096

Product Code:
 
TAR-T9180
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9180-1mg1mg£138.00
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TAR-T9180-2mg2mg£168.00
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TAR-T9180-5mg5mg£229.00
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TAR-T9180-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T9180-10mg10mg£334.00
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TAR-T9180-25mg25mg£519.00
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TAR-T9180-50mg50mg£703.00
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TAR-T9180-100mg100mg£970.00
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Quantity:
TAR-T9180-500mg500mg£1,862.00
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Further Information

Bioactivity:
LUF6096 is a potent allosteric enhancer of the adenosine A3 receptor. LUF6096 is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.
CAS:
1116652-18-6
Formula:
C22H21Cl2N3O
Molecular Weight:
414.33
Pathway:
Neuroscience; GPCR/G Protein
Purity:
1
SMILES:
O=C(NC=1C=C(N=C2C=CC=CC21)NC3=CC=C(Cl)C(Cl)=C3)C4CCCCC4
Target:
Adenosine Receptor

References

Du L, et, al. Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A? adenosine receptor. J Pharmacol Exp Ther. 2012 Jan;340(1):210-7. Heitman LH, et, al. A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor. J Med Chem. 2009 Feb 26;52(4):926-31.