TargetMol

BC1618

Product Code:
 
TAR-T8929
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T8929-1mg1mg£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-5mg5mg£132.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-1mL1 mL * 10 mM (in DMSO)£138.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-10mg10mg£168.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-25mg25mg£269.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-50mg50mg£409.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8929-100mg100mg£575.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
BC1618 is an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling. It promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.
CAS:
2222094-18-8
Formula:
C24H24F3NO2
Molecular Weight:
415.456
Pathway:
Ubiquitination; Chromatin/Epigenetic; Autophagy; PI3K/Akt/mTOR signaling;
Purity:
0.9909
SMILES:
OC(COc1ccc(cc1)C(F)(F)F)CN(Cc1ccccc1)Cc1ccccc1
Target:
Mitophagy; E1/E2/E3 Enzyme; AMPK

References

Yuan Liu, et al. A Fbxo48 inhibitor prevents pAMPK? degradation and ameliorates insulin resistance. Nat Chem Biol. 2021 Mar;17(3):298-306. Marquet R L , Bruin R , Dallinga R J , et al. Modulation of tumor growth by allogeneic blood transfusion[J]. J Cancer Res Clin Oncol, 1986, 111(1):50-53.