TargetMol

Thymidylate Kinase Inhibitor, YMU1

Product Code:
 
TAR-T8864
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8864-1mg1mg£95.00
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Quantity:
TAR-T8864-5mg5mg£128.00
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TAR-T8864-10mg10mg£161.00
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TAR-T8864-25mg25mg£254.00
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Quantity:
TAR-T8864-50mg50mg£365.00
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Quantity:
TAR-T8864-100mg100mg£545.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.
CAS:
902589-96-2
Formula:
C17H22N4O4S
Molecular Weight:
378.45
Purity:
0.9806
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O

References

Dong B , Jaeger A M , Hughes P F , et al. Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1[J]. Science Translational Medicine, 2020, 12(574):eabb5647.