TargetMol

ML 254

Product Code:
 
TAR-T8862
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8862-1mg1mg£111.00
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TAR-T8862-5mg5mg£168.00
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TAR-T8862-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T8862-10mg10mg£229.00
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TAR-T8862-25mg25mg£436.00
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TAR-T8862-50mg50mg£610.00
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Quantity:
TAR-T8862-100mg100mg£838.00
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Further Information

Bioactivity:
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
CAS:
1428630-86-7
Formula:
C18H15FN2O2
Molecular Weight:
310.328
Pathway:
Neuroscience
Purity:
0.9994
SMILES:
CC1(COC1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1
Target:
GluR

References

Zhou Y , Chun A , Gogliotti R D , et al. Pure Positive Allosteric Modulators (PAMs) of mGlu5 with Competitive MPEP-Site Interaction[M]// Probe Reports from the NIH Molecular Libraries Program. PubMed, 2010.