TargetMol

TKIM

Product Code:
 
TAR-T8700
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8700-1mg1mg£177.00
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TAR-T8700-5mg5mg£313.00
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TAR-T8700-1mL1 mL * 10 mM (in DMSO)£335.00
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TAR-T8700-10mg10mg£434.00
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TAR-T8700-25mg25mg£670.00
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TAR-T8700-50mg50mg£914.00
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Quantity:
TAR-T8700-100mg100mg£1,211.00
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Further Information

Bioactivity:
TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.
CAS:
326921-25-9
Formula:
C18H14ClN3O2S
Molecular Weight:
371.84
Pathway:
Membrane transporter/Ion channel
Purity:
0.993
SMILES:
Clc1ccc(cc1)C(=O)NNC(=O)CSc1ccc2ccccc2n1
Target:
Potassium Channel

References

Ma Y , Luo Q , Fu J , et al. Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating[J]. Journal of Medicinal Chemistry, 2020.