TargetMol

HPGDS inhibitor 2

Product Code:
 
TAR-T7948
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7948-1mg1mg£164.00
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TAR-T7948-5mg5mg£303.00
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TAR-T7948-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-T7948-10mg10mg£436.00
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TAR-T7948-25mg25mg£675.00
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TAR-T7948-50mg50mg£922.00
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TAR-T7948-100mg100mg£1,219.00
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TAR-T7948-500mg500mg£2,368.00
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Further Information

Bioactivity:
HPGDS inhibitor 2 is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
CAS:
2101626-26-8
Formula:
C20H24F2N2O3
Molecular Weight:
378.42
Pathway:
Immunology/Inflammation
Purity:
0.9982
SMILES:
CC(C)(O)[C@H]1CC[C@@H](CC1)NC(=O)c1cnc2cc(OC(F)F)ccc2c1
Target:
PGE Synthase

References

Rc A , Dnd A , Yd A , et al. The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure[J]. Bioorganic & Medicinal Chemistry, 2020, 28( 23).