TargetMol

VU6015929

Product Code:
 
TAR-T7862
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T7862-1mg1mg£179.00
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TAR-T7862-5mg5mg£303.00
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TAR-T7862-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-T7862-10mg10mg£436.00
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TAR-T7862-25mg25mg£675.00
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TAR-T7862-50mg50mg£922.00
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Quantity:
TAR-T7862-100mg100mg£1,219.00
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Quantity:
TAR-T7862-500mg500mg£2,368.00
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Further Information

Bioactivity:
VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2)( IC50s of 4.67 nM and 7.39 nM, respectively).
CAS:
2442597-56-8
Formula:
C24H19F4N5O2
Molecular Weight:
485.443
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9807
SMILES:
Cn1ccc(n1)-c1cncc(CNc2cc(ccc2F)C(=O)Nc2cccc(OC(F)(F)F)c2)c1
Target:
Discoidin Domain Receptor (DDR)

References

Jeffries DE, Borza CM, Blobaum AL,et al.Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy[1].ACS Med Chem Lett. 2019 Nov 25 ;11(1):29-33.