TargetMol

TFLLR-NH2

Product Code:
 
TAR-T7573
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7573-1mg1mg£178.00
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TAR-T7573-5mg5mg£484.00
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TAR-T7573-10mg10mg£692.00
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This product comes from: United States.
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Further Information

Bioactivity:
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
CAS:
197794-83-5
Formula:
C31H53N9O6
Molecular Weight:
647.822
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Target:
Protease-activated Receptor

References

Jia Y , Zhang S , Miao L , et al. Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620[J]. Oncology Reports, 2015. Kawabata A , Kuroda R , Kuroki N , et al. Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle[J]. Life Sciences, 2000, 67(20):0-2530. de Garavilla L, et al. Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br J Pharmacol. 2001 Aug;133(7):975-87.