TargetMol

Imeglimin hydrochloride

Product Code:
 
TAR-T7486
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7486-1mg1mg£98.00
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TAR-T7486-2mg2mg£109.00
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TAR-T7486-5mg5mg£134.00
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TAR-T7486-10mg10mg£172.00
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TAR-T7486-1mL1 mL * 10 mM (in DMSO)£245.00
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TAR-T7486-25mg25mg£254.00
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TAR-T7486-50mg50mg£378.00
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TAR-T7486-100mg100mg£535.00
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TAR-T7486-500mg500mg£1,050.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Imeglimin hydrochloride prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
CAS:
775351-61-6
Formula:
C6H14ClN5
Molecular Weight:
191.66
Pathway:
Metabolism; NF-κb; Immunology/Inflammation
Purity:
0.9998
SMILES:
C[C@@H]1N=C(N)NC(N(C)C)=N1.Cl
Target:
Reactive Oxygen Species; Mitochondrial Metabolism

References

Vuylsteke V , Chastain L M , Maggu G A , et al. Imeglimin: A Potential New Multi-Target Drug for Type 2 Diabetes[J]. Drugs in R&D, 2015, 15(3):227-232. Detaille D , Vial G , Borel A L , et al. Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration[J]. Cell death discovery, 2016, 2:15072.