TargetMol

L-685458

Product Code:
 
TAR-T6870
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6870-1mg1mg£168.00
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TAR-T6870-5mg5mg£369.00
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TAR-T6870-1mL1 mL * 10 mM (in DMSO)£514.00
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TAR-T6870-10mg10mg£535.00
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TAR-T6870-25mg25mg£820.00
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TAR-T6870-50mg50mg£1,091.00
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Quantity:
TAR-T6870-100mg100mg£1,428.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
L-685, 458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
CAS:
292632-98-5
Formula:
C39H52N4O6
Molecular Weight:
672.867
Pathway:
Neuroscience; Proteases/Proteasome; Apoptosis; Stem Cells
Purity:
0.9962
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Target:
Apoptosis; Gamma-secretase

References

Shearman MS, et al.Biochemistry. 2000 Aug 1;39(30):8698-8704. Zhang P, et al. Genes Cancer. 2014 May;5(5-6):154-164. Jeon JH, et al. Stem Cells Dev. 2014 Sep 1;23(17):2067-2079.